So what is Skype for Business and what are the differences to Skype for Desktop? Microsoft re-designed and re-branded Microsoft Lync Online to Skype for Business, a virtually identical product to Skype for Desktop which applies to enterprise environments. Skype is great for home and work and lets you connect and communicate with millions of people. A number of companies, including Skype, produce dedicated Skype phones. The service is available for desktop computers, notebook and tablet computers and other mobile devices, including mobile phones. In addition to standard telephone calls, Skype enables file transfers, texting, video chat and video-conferencing. Skype is an IP telephony service provider that offers free calling between subscribers and low-cost calling to people who don’t use the service.